死亡因子4样蛋白2抗体-抗体-抗体-生物在线
北京索莱宝科技有限公司
死亡因子4样蛋白2抗体

死亡因子4样蛋白2抗体

商家询价

产品名称: 死亡因子4样蛋白2抗体

英文名称: Mortality Factor 4 like 2

产品编号: bs-17723R

产品价格: null

产品产地: 北京

品牌商标: BIOSS

更新时间: 2026-01-27T09:36:11

使用范围: WB=1:100-500,ELISA=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,

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Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.